Education & Evidence
Links to pages and articles supporting current
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Estradiol for Women
Estradiol (E2) is an important hormone for both men and women
It is one of the 3 primary estrogens made by women throughout their life, including estriol and estrone. E2 is the most potent of the 3, being up to 80x stronger than estriol. It is the loss of this hormone in menopause that increases a woman's risk for heart disease, cancers, stroke osteoporosis, and diabetes.
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Bioidentical estradiol is not the same as conjugated equine estrogens (CEE) and does not carry the same risk factors. CEE is 15% estradiol and 85% nonbioidentical estrogens with much higher potency and thrombogenic.
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Estrogen and lipids
The Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
Conclusions: Estrogen alone or in combination with a progestin improves lipoproteins and fibrinogen.
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Estrogen and atherosclerosis
Estrogen in the prevention of atherosclerosis
Conclusions: Rate of progression of subclinical atherosclerosis was slower in healthy menopausal women taking estrogen but not in women taking lipid-lowering medication.
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Estrogen and atherosclerosis
Estrogen in the prevention of atherosclerosis
Conclusions: Rate of progression of subclinical atherosclerosis was slower in healthy menopausal women taking estrogen but not in women taking lipid-lowering medication.
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